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目的 :了解宫颈病变的患者的阴道菌群分布情况 ,探讨宫颈不同病变对阴道微生态环境的影响。方法 :采用Mi croScanautoSCAN 4细菌鉴定系统分析 85例宫颈病变患者阴道分泌物中的分离出的菌株情况。结果 :共检出需氧菌 8种 ,主要检出的异常菌群为大肠埃希氏菌。宫颈有病变患者的乳酸杆菌检出率为 2 8 2 % ,大大低于文献报道正常体检妇女 (74 6% ) ,两者相比较 ,有显著性差异 (P <0 0 5 )。其异常需氧菌群的检出率为 3 6 5 % ,较文献报道正常体检妇女 (2 4 3 % )及阴道炎妇女(2 4 0～ 2 7 6% )高 ,有显著性差异 (P <0 0 5 )。宫颈非恶性病变患者与宫颈恶性病变患者的异常需氧菌群检出率分别为2 3 1% ,2 9 2 % ,差异无统计学意义 (P >0 0 5 ) ;阴道分泌物性质为血性、脓性者其阴道异常需氧菌群的检出率分别为 2 7 8% ,5 0 % ,差异无统计学意义 (P >0 0 5 )。结论 :宫颈病变可影响阴道的微生态环境 ,造成阴道内乳酸杆菌的大量减少 ,异常需氧菌群增加。但阴道菌群分布与宫颈疾病的良恶性无关
Objective: To understand the distribution of vaginal flora in patients with cervical lesions and to explore the effects of different cervical lesions on vaginal microenvironment. Methods: Mi croScanautoSCAN 4 bacterial identification system analysis of 85 cases of cervical lesions in patients with vaginal discharge isolated strains. Results: Eight kinds of aerobic bacteria were detected. The main abnormal bacteria were Escherichia coli. The detection rate of lactobacilli in patients with cervical lesions was 28.2%, which was significantly lower than that of the normal physical examination women (74.6%) reported in the literature. There was a significant difference between the two groups (P <0.05). The detection rate of abnormal aerobic bacteria group was 36.5%, which was higher than that of the normal physical examination women (24.3%) and vaginitis women (240 ~ 276%) reported in the literature (P <0 0 5). The detection rates of abnormal aerobic groups in cervical non-malignant lesions and cervical malignant lesions were 23% and 292%, respectively, with no significant difference (P> 0.05). The vaginal secretions were bloody , And the detection rate of abnormal vaginal aerobes in pyogenic group were respectively 27.8% and 50%, the difference was not statistically significant (P> 0.05). Conclusion: Cervical lesions can affect the microenvironment of the vagina, resulting in a substantial reduction of vaginal lactobacilli, abnormal aerobic flora increased. However, the distribution of vaginal flora and cervical disease has nothing to do with the benign and malignant