患者,男性,49岁,因头晕乏力2年余,近半年来症状日渐加重,有时下肢浮肿低烧,发病无鼻衄及牙齿出血,无骨骼疼痛,在当地诊断为“贫血”,曾服硫酸亚铁及其它补血药治疗无效,本人无特殊药物及放射线接触史,亲属子女无类似病史。体检:体温37℃, Patients, male, 49 years old, due to dizziness, fatigue more than 2 years, the symptoms gradually increased in the past six months, and sometimes lower extremity edema, morbidity and nose bleeding and no bleeding, no skeletal pain, diagnosed locally as “anemia” Iron and other blood drug treatment is invalid, I have no special drug and radiation exposure history, relatives and children without a similar history. Physical examination: body temperature 37 ℃,