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目的研究经尿道前列腺绿激光汽化术(PVP)治疗良性前列腺梗阻(BPO)伴帕金森病(PD)的疗效及安全性。方法选择2008年7月至2016年5月收治的BPO伴PD患者20例,65~75岁,平均(69.85±3.12)岁,平均国际前列腺症状评分(IPSS)(23.40±5.89)分,平均最大尿流率(Qmax)(5.75±1.71)m L/s。患者均出现排尿困难症状并确诊为BPO伴PD,均排除合并多系统萎缩病(MSA),采用配对t检验进行组间比较,评估行PVP手术的疗效。结果 20例手术均顺利完成,平均手术时间(66.3±13.10)min,术后3个月患者平均IPSS(7.10±2.59)分,Qmax(14.03±4.40)m L/s,均较术前明显改善。4例患者术后出现急迫性尿失禁,经过盆底肌训练后好转。结论 PVP是BPO伴PD患者解除尿路梗阻及改善症状的一种安全有效的治疗方法。
Objective To study the efficacy and safety of transurethral vaporization of the prostate (PVP) in the treatment of benign prostatic obstruction (BPO) with Parkinson’s disease (PD). Methods From July 2008 to May 2016, 20 BPO patients with PD, 65 to 75 years old, with an average of (69.85 ± 3.12) years and an average of IPSS (23.40 ± 5.89) Urine flow rate (Qmax) (5.75 ± 1.71) m L / s. All patients developed symptoms of dysuria and were diagnosed as BPO with PD. All patients with multiple system atrophy (MSA) were excluded. Paired t-test was used to compare between groups to evaluate the efficacy of PVP. Results All of the 20 cases were successfully performed with mean operative time (66.3 ± 13.10) min and mean IPSS (7.10 ± 2.59) and Qmax (14.03 ± 4.40) m L / s at 3 months postoperatively, respectively, . In 4 patients, urinary incontinence occurred urgently after pelvic floor muscle training. Conclusion PVP is a safe and effective treatment for relieving urinary tract obstruction and improving symptoms in BPO patients with PD.