对１２年收治的资料完整的小儿肾母细胞瘤（ＷＴ）６７例统一进行形态学分类，统计流行病学、形态学、临床症状、实验室检查、治疗等２９个与ＷＴ有关的因素并输入ＣＥＣｏｘ模型分析，结果有８个单因素，即分型、分化、肿瘤包膜浸润、血管瘤栓、淋巴结转移、治疗方式等与ＷＴ预后有关。多因素Ｃｏｘ模型分析绍果：临床分期、组织分化、治疗方式三个因素与ＷＴ预后有关。讨论Ｃｏｘ模型在预后分析应用中的特点，多因素相互间的内在联系、互相制约的关系，以正确认识并指导临床。 Sixty-seven cases of pediatric nephroblastoma (WT), with complete data of 12 years, were collected for morphological classification and 29 WT-related factors such as epidemiology, morphology, clinical symptoms, laboratory tests, and treatment were collected and entered CECox model analysis, the results of 8 single factors, namely, type, differentiation, tumor envelope invasion, tumor thrombus, lymph node metastasis, treatment and other related to the prognosis of WT. Multivariate Cox model analysis Shaoguo: clinical stage, tissue differentiation, treatment of three factors and prognosis of WT. Discusses the characteristics of Cox model in the application of prognostic analysis, the inter-relationship between multiple factors and mutual restraint, to correctly understand and guide the clinical.