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本文报道在11条犬以明胶海绵、17条犬以液态硅橡胶栓塞肝、肾和胃肠道动脉后的病理变化。 以明胶海绵栓塞者,肉眼肾血管内未见栓子,镜检肾小动脉内发现有海绵栓子;以液态硅橡胶栓塞者,肉眼或镜下从肾动脉主干及其各级分支中和肾小球毛细血管襻内均可见大量硅橡胶栓子。肾动脉栓塞1天,肾实质内未见梗死形成;3～4天时,肾脏内出现多发性梗死灶;栓塞1周时,梗死灶周围纤维母细胞增生较活跃,并形成少量胶原纤维,伴以中性白细胞为主的炎细胞浸润;栓塞2～3周时,肾表面出现多发性凹陷,胶原纤维形成增多;5～6周后,梗死灶趋于疤痕化。
This article reports 11 dogs with gelatin sponge, 17 dogs with liquid silicone rubber embolization of liver, kidney and gastrointestinal artery pathological changes. With gelatin sponge embolism, there was no embolus in the macroscopic renal vessels, and sponge emboli were found in the renal arterioles in the microscopic examination. In the cases of embolism with liquid silicone rubber, the kidney and its branches at the macroscopic or microscopic A large number of silicone rubber plugs can be seen in the capillaries of the pellets. One day after embolization of the renal artery, no infarction was found in the renal parenchyma. In the third to fourth days, there were multiple infarcts in the kidneys. One week after the embolization, the fibroblasts around the infarct area became more hyperplastic and formed a small amount of collagen fibers, Neutrophil-based infiltration of inflammatory cells; 2-3 weeks after embolization, multiple surface degeneration on the surface of the kidney, collagen fibers increased; 5 to 6 weeks, the infarct tends to scarring.