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目的:调查了解陆军某部新兵幽门螺杆菌(HP)感染情况及其与相关疾病的关系。方法:随机整群抽取陆军某部新兵677例,采用13C尿素呼气试验(13C-UBT)检测HP感染情况,同时采用包括全国幽门螺杆菌研究问卷调查表、功能性消化不良(FD)症状自评量表、肠易激综合征(IBS)相关症状调查表、胃食管反流病(GERD)问卷、症状自评量表(SCL-90)等进行问卷调查,分析HP感染与FD、IBS、GERD等疾病的关系。结果:陆军某部新兵HP总体感染率40.24%,FD、IBS及GERD患病率分别为23.78%、37.96%、19.94%,SCL-90阳性率22.30%。入伍前居住地为华东地区、华中地区和华北地区新兵的HP感染率分别为35.84%、38.62%和46.06%,不同地区HP感染率差异不显著(P>0.05)。是否为家庭独生子、入伍前家庭是否饲养动物的新兵HP感染率均差异不显著(P>0.05)。HP阳性新兵FD、IBS患病率及SCL-90阳性率分别为28.57%、43.22%和29.30%,分别显著或非常显著高于HP阴性新兵的20.54%、34.41%和17.57%(P<0.05,P<0.01);HP阳性新兵GERD患病率21.25%,HP阴性者患病率为19.06%,两组差异不显著(P>0.05)。结论:某部新兵HP总体感染率较前有下降趋势,但IBS患病率显著高于普通人群;HP感染的新兵其FD和IBS患病率显著升高、心理健康水平显著降低。
OBJECTIVE: To investigate the relationship between Helicobacter pylori (HP) infection and related diseases in a recruited Army Army. Methods: A total of 677 recruits from the army were recruited in a randomized cluster. The 13C urea breath test (13C-UBT) was used to detect the HP infection. At the same time, the questionnaires including the National Helicobacter Pylori Questionnaire, the Functional Dyspepsia (FD) IBS, GERD and SCL-90 were investigated by questionnaires. The prevalence of HP infection was significantly higher than that of FD, IBS, GERD and other diseases. Results: The overall infection rate of HP was 40.24%. The prevalences of FD, IBS and GERD were 23.78%, 37.96% and 19.94%, respectively. The positive rate of SCL-90 was 22.30%. The HP infection rates of recruits who lived in east China, north China and central China were 35.84%, 38.62% and 46.06%, respectively. There was no significant difference in HP infection rates among different regions (P> 0.05). There was no significant difference (P> 0.05) in the prevalence of HP infection among recruits whose families were singletons and whether their families were singletons or not. The prevalence of FD, IBS and the positive rate of SCL-90 in HP-recruited recruits were 28.57%, 43.22% and 29.30%, respectively, significantly higher than that of HP negative recruits (20.54%, 34.41% and 17.57%, respectively; P < P <0.01). The prevalence of GERD in HP positive recruits was 21.25%, and the prevalence of HP negative was 19.06%. There was no significant difference between the two groups (P> 0.05). Conclusion: The prevalence of HP in a certain recruits decreased compared with the previous one, but the prevalence of IBS was significantly higher than that of the general population. The recruits with HP infection had significantly higher prevalence of FD and IBS and significantly lower mental health.