论文部分内容阅读
Ig A肾病(Ig AN)是指肾小球系膜区以Ig A或Ig A沉积为主的原发性肾小球疾病,因其在临床治疗中频繁出现而引起世界范围内的广泛研究。尽管Ig A肾病的具体发病机制尚未明确,但越来越多的临床案例表明幽门螺杆菌(Hp)感染对Ig A肾病的产生及发展有重要影响,可能是Ig A肾病的潜在诱因之一。本论文基于国内外的研究进展,在已有的研究基础上进一步综述了幽门螺杆菌感染对Ig A肾病发生、发展的影响及其潜在作用机制。
Ig A nephropathy (Ig AN) is a primary glomerular disease characterized mainly by IgA or IgA deposition in the mesangial area, which has led to extensive worldwide research due to its frequent occurrence in clinical practice. Although the exact pathogenesis of IgA nephropathy is not yet clear, more and more clinical cases show that H.pylori infection has a significant impact on the development and progression of IgA nephropathy, which may be one of the potential causes of IgA nephropathy. Based on the research progress at home and abroad, based on the existing research, this paper further reviewed the influence of Helicobacter pylori infection on the occurrence and development of IgA nephropathy and its potential mechanism.