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近年来甲型肝炎(甲肝)ALT 迁延不愈的患者有逐年增多的趋势,现将近5年全部住院甲肝病例有关资料报道如下。一、临床资料按1995年修订的病毒性肝炎防治方案中的诊断标准,收集抗-HAV-IgM 阳性的1991年1月～1995年12月全部甲肝住院患者463例,各年依序为103例,138例,103例,53例和66例。各年份组间性别年龄构成差别无显著意义(P 值>0.05)。年龄方面仍以青少年为多(43.94%～69.92%),25岁以上较少,但1995年却有明显增多(P值<0.05)。二、随访结果各年份组病例随访结果见附表。随访无 HBV 重叠感染9例患者出院后在无疲劳、饮酒及损肝药物等诱因下,ALT 异常达8～21个月。另有4例无重叠感染病例在 ALT<140U/L 后上班、上学等疲劳后 ALT 急剧上升至281～876U/L。其中2例胆红素
In recent years, hepatitis A (hepatitis A) patients with delayed healing of ALT have an increasing trend, now nearly 5 years of hospitalized cases of hepatitis A are reported as follows. First, the clinical data According to the 1995 revision of the viral hepatitis prevention and control programs in the diagnostic criteria, collect anti-HAV-IgM positive January 1991 ~ December 1995 463 cases of hospitalized patients with hepatitis A, the order of 103 cases , 138 cases, 103 cases, 53 cases and 66 cases. There was no significant difference in sex and age between groups (P> 0.05). There are still many adolescents (43.94% -69.92%) in age, but less than 25 years old, but there was a significant increase in 1995 (P <0.05). Second, the follow-up results in each group of patients follow-up results, see the attached table. Follow-up No overlap HBV infection in 9 patients after discharge in the absence of fatigue, alcohol and liver damage drugs and other incentives, ALT abnormalities up to 8 to 21 months. Another 4 cases of non-overlapping infections in ALT <140U / L after work, school and other fatigue ALT rose sharply to 281 ~ 876U / L. Two cases of bilirubin