患儿男,10岁,以“食欲亢进,进行性肥胖2年”为主诉入院。近2年来,患儿每天进主食约1000克及少量肉类和蔬菜。时有头痛,活动后气喘,无恶心呕吐及多饮多尿。体重每年增长10公斤左右。动作欠灵活,语言不畅,记忆力减退,学习成绩下降。既往身体健康,否认头颅外伤史、颅内感染史及传染病史。父母非近亲结婚。体检:体温36.5℃,脉搏102次/分,血压14/11kPa,身高143cm,体重65kg。神志清晰,全身呈均 Children male, 10 years old, with “appetite hyperthyroidism, progressive obesity 2 years ” mainly for admission. The past two years, children daily staple food about 1000 grams and a small amount of meat and vegetables. When there are headaches, wheezing after activities, no nausea and vomiting and polydipsia. Weight gain of about 10 kg per year. Action is not flexible, poor language, memory loss, academic performance decline. Past physical health, deny skull trauma history, history of intracranial infection and infectious disease history. Parents marry non-relatives. Physical examination: body temperature 36.5 ℃, pulse 102 beats / min, blood pressure 14 / 11kPa, height 143cm, weight 65kg. Conscious, whole body was average