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目的 :了解传染性非典型肺炎 (SARS)主要传播因素及危险因素。方法 :应用 1:1配比的病例对照研究方法对 SARS病例与正常对照进行研究。采用条件 L ogistic回归分析方法进行资料分析。结果 :单因素分析结果表明 X1(发病前 2 0 d内没有到外市 (县 )旅行史 )、X2 (发病前 2 0 d内没有到过医院 )、X19(发病前没有患其它疾病 )对 SARS的发病具有保护作用 ,其 OR值分别为 0 .4 9(0 .2 4～ 0 .96 )、 0 .4 4 (0 .2 7～ 0 .71)、 0 .39(0 .2 3～ 0 .6 8)。而 X10 (发病前患有高血压病 )和 X5 (发病前 2 0 d内与确诊 (或疑似 )非典病例接触 )具有较强的危险性 ,它们的 OR值分别为 3.6 7(1.0 2～ 13.14 )、11.2 0 (3.36～ 37.35 )。而多因素分析中 ,只有 X1、X5、X7(住宅类型 ) 3个因素进入模型 ,其 OR值分别为 0 .32 (0 .12～0 .87)、 2 2 .93(2 .5 4～ 2 0 7.0 2 )、 1.93(0 .75～ 4 .95 )。结论 :SARS的发病与接触史、居住在居民楼、外出旅行史有关。高血压病人是高危人群 ,应加强防护。
Objective: To understand the main transmission factors and risk factors of SARS. Methods: A case-control study with 1: 1 ratio was used to study SARS cases and normal controls. The conditional L ogistic regression analysis method was used to analyze the data. Results: The results of univariate analysis showed that X1 (no travel history outside city (county) within 20 days before onset), X2 (no hospital within 20 days before onset), X19 (no other disease before onset) The incidence of SARS has a protective effect, the OR values were 0.49 (0.24 ~ 0.96), 0.44 (0.27 ~ 0.71), 0.39 (0.23 ~ 0 .6 8). While X10 (pre-morbid with hypertension) and X5 (contact with confirmed (or suspected) SARS within 20 days before onset) were highly risky and their OR values were 3.6 7 (1.0 2 ~ 13.14 ), 11.2 0 (3.36 ~ 37.35). In the multivariate analysis, only the three factors of X1, X5 and X7 (residential type) entered the model with OR values of 0.32 (0.12-0.87) and 22.93 2 0 7.0 2), 1.93 (0.75 ~ 4.95). Conclusion: The incidence of SARS and exposure history, living in residential buildings, travel history related. Hypertensive patients are at high risk, should strengthen protection.