广泛应用抗生素常产生不良的免疫学反应,从Ⅰ型～Ⅳ型的过敏反应都能产生。青霉素、四环素和磺胺嘧啶均能引起类似自身免疫病的疾患。已经指出,用抗生素后可改变血清补体的杀菌活性。本文研究抗生素对补体系统的作用。选择糖尿病、心肌梗塞、伤寒、干性胸膜炎,风湿性舞蹈病和支气管哮喘等23例住院病人,给予四环素、氯 Widely used antibiotics often produce unhealthy immunological reactions, from type Ⅰ to type Ⅳ can produce allergic reactions. Penicillin, tetracycline and sulfadiazine cause disorders like autoimmune diseases. It has been pointed out that antibiotics can alter the bactericidal activity of serum complement. This article studies the effect of antibiotics on the complement system. Twenty-three inpatients, including diabetes mellitus, myocardial infarction, typhoid fever, dry pleurisy, rheumatic chorea and bronchial asthma, were given tetracycline, chlorine