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迄今为止,用于人类生育控制的雌、孕激素避孕药,其作用机理主要是抑制排卵及阻碍受精、干扰孕卵着床等。而米非司酮(RU 486)作为一种抗孕激素是从子宫受体水平干扰孕酮对妊娠的支持作用,有人称该药的研制成功“开创了一个生育控制药物的新时代”是今后从甾体化合物中寻找抗生育药物的一个发展方向。它与前列腺素序贯应用已被证实是一种安全有效
So far, the estrogen and progestin contraceptive used for the control of human birth mainly acts to inhibit ovulation and prevent fertilization and interfere with the implantation of the pregnant egg. While the use of mifepristone (RU 486) as an antiprogestin interferes with the progestational support of progesterone at the uterine receptor level, it is said that the drug was successfully developed “to create a new era of fertility control drugs” in the future Looking for anti-fertility drugs from steroids in a development direction. Its sequential use with prostaglandin has proven to be a safe and effective method