目的探讨氯沙坦和贝那普利联合治疗糖尿病肾病的临床效果。方法选择72例内分泌科门诊及住院病例,随机分为观察组和对照组,观察组应用氯沙坦和贝那普利联合治疗,对照组单用贝那普利治疗,比较两组疗效和不良反应。结果观察组治疗总有效率为94%,对照组治疗总有效率为56%,差异有统计学意义(P<0.05)。结论氯沙坦和贝那普利联用治疗DN能明显提高疗效,而且耐受性和安全性较好,值得推广应用。 Objective To investigate the clinical effect of losartan and benazepril in the treatment of diabetic nephropathy. Methods 72 cases of endocrinology outpatient and inpatient cases were randomly divided into observation group and control group. The observation group was treated with losartan and benazepril. The control group was treated with benazepril alone. reaction. Results The total effective rate of observation group was 94%, while the total effective rate of control group was 56%, the difference was statistically significant (P <0.05). Conclusion Losartan and benazepril combined treatment of DN can significantly improve the efficacy, and tolerance and safety is good, it is worth promoting the application.