It is important to know the maximum solid solubility(Cmax) of various transition metals in a metal when one designs multi-component alloys. There have been several semi-empirical approaches to qualitatively predict the Cmax, such as Darken-Gurry(D-G) theorem, Miedema-Chelikowsky(M-C) theorem, electron concentration rule and the bond-parameter rule. However, they are not particularly valid for the prediction of Cmax. It was developed on the basis of energetics of alloys as a new method to predict Cmax of different transition metals in metal Ti, which can be described as a semi-empirical equation using the atomic parameters, i e, electronegativity difference, atomic diameter and electron concentration. It shows that the present method can be used to explain and deduce D-G theorem, M-C theorem and electron concentration rule.