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为了寻找有效的辐射防护药,本文报告了有效防护剂5-甲氧基色胺的吲唑类似物及有关衍生物的合成。经药理试验证明5-甲氧基吲唑乙胺及5-羟吲唑乙胺具有明显的抗放活性。
In order to find an effective radioprotective drug, this paper reports the synthesis of indazole analogs and related derivatives of 5-methoxytryptamine, an effective protective agent. Pharmacological tests showed that 5-methoxyindazole ethylamine and 5-hydroxyindazolamine had significant anti-release activity.