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利用细胞杂交技术制备的单克隆抗体可检测各种T 细胞抗原。作者采用一组市售的单克隆抗体(包括HLA-DR、Leu-1,OKT-3、Leu-2,OKT-8,Leu-3和 OKT-4等)对35例淋巴细胞白血病和部分淋巴细胞系的细胞表面抗原进行了检测,同时测定它们的膜表面球蛋白、胞浆免疫球蛋白、E 玫瑰花结形成(EFRC)和普通急性淋巴细胞白血病(cALL)抗原等。在此基础上对淋巴细胞白血病作了免疫学分型的尝试。结果 12例急性淋巴细胞白血病(ALL)可分3
Monoclonal antibodies prepared by the cell hybridization assay can detect a variety of T cell antigens. The authors used a panel of commercially available monoclonal antibodies (including HLA-DR, Leu-1, OKT-3, Leu-2, OKT-8, Leu-3 and OKT-4 etc.) to treat 35 cases of lymphocytic leukemia and partial lymph The cell surface antigens of cell lines were detected and their membrane surface globulin, cytoplasmic immunoglobulin, E-rosette formation (EFRC) and common acute lymphoblastic leukemia (cALL) antigens were detected. On this basis, immunological typing of lymphocytic leukemia was attempted. Results 12 cases of acute lymphoblastic leukemia (ALL) can be divided into 3