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Fas(Apo- 1/CD95 )属 TNFR/NGFR家族 ,为“死亡受体”,因为其介导凋亡的作用倍受人们关注。目前对 Fas抗原及其基因的结构与功能研究已较为清楚 ,Fas的变异体及 Fas基因突变的形成和功能研究也取得一定的进展。
Fas (Apo-1 / CD95) belongs to the TNFR / NGFR family and is a “death receptor” because its role in mediating apoptosis is of great concern. At present, the study on the structure and function of Fas antigen and its gene has been more clear, and some progress has been made in the study of the formation and function of Fas and Fas gene mutations.