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随着免疫学的进展,人们认为肿瘤的经过不单取决于肿瘤本身的恶性程度,而是肿瘤的侵袭和宿主的抵抗相互作用的结果。宿主的抵抗作用,主要是免疫反应,可能在预后上有重要作用。目前,关于淋巴结的各区域在免疫反应中的作用,大体上已经明确,如生发中心是B细胞的活动部位,参与体液免疫反应,付皮质区是T细胞的活动部位,参与细胞免疫反应。因之,观察淋巴结的组织学所见以及肿瘤间质的淋巴细胞浸润和淋
With the advancement of immunology, it is believed that the progression of tumors depends not only on the degree of malignancy of the tumor itself but also as a result of the interaction of tumor invasion and host resistance. The host’s resistance, mainly immune response, may play an important role in the prognosis. At present, the role of various regions of the lymph node in the immune response has been generally clear. For example, the germinal center is the active site of B cells and participates in the humoral immune response. The cortical area is the active site of T cells and participates in cellular immune responses. Therefore, observing the histological findings of lymph nodes and lymphocytic infiltration and leaching of tumor stroma