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二巯基丙醇注射液为常用的重金屬解毒药之一,我国药典列为法定药品,目前在我国工矿等医疗單位的临床上应用較多。关于本品的詳細操作方法,国内文献向未見記载,作者曾經多次配制,現將配制过程以及影响本品質量的某些关鍵問題的初步經驗介紹于后,以供有关生产單位参考。二巯基丙醇的理化性質二巯基丙醇的結構,旣有羟基,又含巯基,因此就具备醇和硫醇的双重性質,其結構式如下:
Dimercaptopropanol injection is one of the commonly used heavy metal antidotes, our country pharmacopoeia as statutory drugs, currently in the clinical application of mines and other medical units in our country more. The detailed operation method of this product, the domestic literature to the unrecorded records, the author has repeatedly formulated, now the preparation process and the impact of the quality of some of the key issues of the initial experience introduced later, for the reference of the relevant production units . The physical and chemical properties of dimercaptopropanol Dimercaptopropanol structure, there is a hydroxyl group, but also contains a mercapto group, and therefore have the dual nature of alcohol and thiol, the formula is as follows: