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目的研究经阴道超声联合肿瘤标志物检测对卵巢良恶性肿瘤的诊断价值。方法选择某院2008年5月~2011年5月收治的120例卵巢肿瘤患者作为研究对象,其中恶性肿瘤10例,良性肿瘤110例,所有患者均采用阴道超声检查后记录其肿块的超声征象,同时采用化学发光法检查患者体内肿瘤标记物CA125的含量,并对结果行统计学分析。结果阴道超声检出的准确率为90%(108),经CA125标记物检出的准确率为84.16%(101),两者联合诊断的准确率为95%(115),联合诊断准确率显著高于二者单独使用,差异有统计学意义(χ2=1.595,P﹤0.01)。结论经阴道超声检查卵巢良恶性肿瘤,二维图像可清晰观察肿瘤内部结构及彩色多普勒观察肿瘤血流分布及频谱特征,结合检测外周血中CA125水平可以更为准确地评价卵巢肿瘤的性质,从而弥补单独使用两种方法之一的不足。阴道超声联合肿瘤标志物对卵巢肿瘤可以较好地鉴别出良恶性肿瘤的性质,值得广泛用于临床使用。
Objective To investigate the value of transvaginal ultrasound combined with tumor markers in the diagnosis of benign and malignant ovarian tumors. Methods A total of 120 patients with ovarian tumors who were treated in our hospital from May 2008 to May 2011 were selected as the study subjects, including 10 malignant tumors and 110 benign tumors. All patients underwent ultrasound examination of the vagina to record the ultrasound signs of the tumors, The chemiluminescence method was used to examine the content of tumor marker CA125 in patients and the results were statistically analyzed. Results The accuracy of vaginal ultrasound was 90% (108). The accuracy of detection by CA125 was 84.16% (101). The diagnostic accuracy of combined diagnosis was 95% (115). The diagnostic accuracy was significantly higher Higher than the two alone, the difference was statistically significant (χ2 = 1.595, P <0.01). Conclusions Transvaginal ultrasonography can be used to detect benign and malignant ovarian tumors. The two-dimensional images can clearly observe the internal structure of the tumor and observe the distribution of tumor blood flow and spectral characteristics by color Doppler. Combining with the detection of CA125 levels in peripheral blood, we can evaluate the ovarian tumor more accurately , To make up for the lack of use of either method alone. Vaginal ultrasound combined with tumor markers on ovarian tumors can better identify the nature of benign and malignant tumors, it is widely used in clinical use.