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【目的】分析西安地区儿童副流感病毒(parainfluenza virus,PIV)感染情况及与中性粒细胞减少的关系。【方法】采用酶联免疫吸附(ELISA)法检测血清中副流感病毒特异性IgM抗体(PIV-IgM),血细胞分析仪检测外周血白细胞。【结果】1～6岁年龄组PIV感染阳性率较其他年龄组明显升高,1～3岁年龄组中性粒细胞减少症发生率较高,PIV感染与中性粒细胞减少的发生关系密切。【结论】西安地区儿童呼吸道PIV感染阳性率较高,常规进行病原血清特异性抗体检测有助于临床医生合理用药。
【Objective】 To analyze the relationship between parainfluenza virus (PIV) infection and neutropenia in children in Xi’an. 【Methods】 Serum parainfluenza virus specific IgM antibody (PIV-IgM) was detected by enzyme-linked immunosorbent assay (ELISA), and peripheral blood leukocytes were detected by hematology analyzer. 【Results】 The positive rate of PIV infection in 1 ~ 6 years old group was significantly higher than that in other age groups. The incidence of neutropenia in 1 ~ 3 years old group was higher, and the incidence of PIV infection was closely related to the neutropenia . 【Conclusions】 The positive rate of respiratory tract PIV infection in children in Xi’an is high. It is helpful for clinicians to use drugs routinely to carry out pathogen-specific serum antibody tests.