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干细胞因子 (SCF)是一种重要的多功能细胞因子 ,它能刺激早期干细胞的增殖及定居 ,单用或伍用其它细胞因子能刺激造血集落细胞的增生、增大 ,为人类重要的造血生长因子之一 ,可应用于致死性急性照射后的造血恢复、放化治疗和骨髓功能衰竭后贫血及其它难治性贫血的治疗等。现已实现了SCF的基因克隆及基因工程表达。
Stem cell factor (SCF) is an important multifunctional cytokine that stimulates the proliferation and colonization of early stem cells. Stimulation of proliferation and colonization of hematopoietic colony cells can be stimulated by other cytokines alone or in combination with other important cytokines One of the factors, can be applied to hematopoietic recovery after acute lethal irradiation, radiotherapy and treatment of anemia and other refractory anemia after bone marrow failure and so on. Has now achieved SCF gene cloning and gene engineering.