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日本诊断恶性高热的标准是最高体温达40℃以上,或体温在38℃以上并迅速增高(每15分钟升高0.5℃以上),同时伴有肌肉强直、脉速、呼吸性和代谢性酸中毒、发绀等症状。向田统计1961年以来210例恶性高热中,男165人,女44人(1例不明)。据某集团资料1976～1985的10年麻醉例数中,恶性高热共发生121例。日本全麻病例恶性高热发生率为6万分之1,而英国为20万分之1,丹麦为22万分之1。恶性高热发生率不同,可能与各国诊断标准和麻醉总数统计的方法不同有关,因此,只做单纯比较是困难的。
Japan’s criteria for the diagnosis of malignant hyperthermia are those with a maximum body temperature of 40 ° C or above, or a rapid increase in body temperature above 38 ° C (above 0.5 ° C every 15 minutes), with muscle rigidity, pulse rate, respiratory and metabolic acidosis , Cyanosis and other symptoms. To field statistics since 1961 210 cases of malignant fever, 165 males and 44 females (1 case unknown). According to a group of data from 1976 to 1985, 10 cases of anesthesia in a total of 121 cases of malignant hyperthermia. The incidence of malignant hyperthermia in general anesthesia cases in Japan was 1 in 60,000, compared with 1 in 200,000 in the United Kingdom and 1 in 220,000 in Denmark. The incidence of malignant hyperthermia varies and may be related to different diagnostic criteria and the total number of anesthesia methods in different countries. Therefore, it is difficult to make a simple comparison.