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HP感染大多在儿童期或青春期获得,细菌根治后6～12个月慢性炎症消失,否则,慢性胃炎可持续多年甚至终生存在。本文调查了HP胃炎对胃粘膜的长期影响。 研究对象共107例,于1979～1983年和1992～1993年进行两次内镜活检组织学和血清HP抗体检查。平均观察时间11.5年(10～13年)。 结果:首次检查:HP阴性49例,其中萎缩性胃炎7例(14％),6例伴肠化生;HP阳性58例,均为慢性胃炎,其中萎缩性胃炎14例(24％),6例伴肠化生。第二次检查:HP阴性
Most HP infections are obtained in childhood or adolescence. Chronic inflammation disappears 6 to 12 months after the bacteria are cured. Otherwise, chronic gastritis persists for years or even for a lifetime. This article investigates the long-term effects of HP gastritis on gastric mucosa. A total of 107 subjects, two in 1979 ~ 1983 and 1992 ~ 1993 endoscopic biopsy histology and serum HP antibody examination. The average observation time of 11.5 years (10 to 13 years). Results: For the first time, 49 cases were negative for HP, of which 7 cases were atrophic gastritis (14%), 6 cases were associated with intestinal metaplasia and 58 cases were positive for HP. All of them were chronic gastritis, including 14 cases of atrophic gastritis (24%), 6 Case of intestinal metaplasia. The second check: HP negative