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【目的】了解金华金华婴幼儿25-羟维生素D(25-OHD)水平,关注维生素D缺乏性佝偻病。【方法】对来院儿科门诊检查的0~6岁4 836例儿童,采用酶联免疫法进行25-OHD检测,对结果进行统计分析。【结果】4 836例儿童中25-OHD水平较为足够(合适水平)的为1 564例,占32.3%;相对缺乏(临界水平)的为2 520例,占52.1%;缺乏的为752例,占15.6%。后两者占总人数的68.0%,以0~2岁婴幼儿为主,不同年龄组25-OHD均值差异有统计学意义(F=26.45,P<0.05)。性别间25-OHD水平差异无统计学意义(t=1.340,P>0.05);区域间25-OHD水平差异有统计学意义(t=6.417,P<0.05)。【结论】应加强婴幼儿的户外活动并系统管理。
【Objective】 To investigate the level of 25-OHD in infants in Jinhua Jinhua and to observe the vitamin D deficiency rickets. 【Methods】 A total of 4836 children aged 0-6 years old who came to our hospital for pediatric outpatient examination were tested for 25-OHD by enzyme-linked immunosorbent assay and the results were statistically analyzed. 【Results】 A total of 1 564 cases (32.3%) of the 2536 children with relatively adequate 25-OHD levels were found (appropriate level), 5220 cases (52.1%) were relatively deficient (critical level), 752 cases were deficient, Accounting for 15.6%. The latter two accounted for 68.0% of the total number of patients, mainly from 0 to 2 years old infants and young children. The mean 25-OHD in different age groups was significantly different (F = 26.45, P <0.05). There was no significant difference in the 25-OHD level between the sexes (t = 1.340, P> 0.05). There was a significant difference in the 25-OHD level between the sexes (t = 6.417, P <0.05). 【Conclusion】 The outdoor activities of infants and young children should be strengthened and managed systematically.