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本文通过组间对比,观察了输精管结扎对垂体-性腺轴的远期影响。对照组(未扎)289人,结扎组515人,两组年龄均在30～65岁,结扎后年数为3～25年,与同年龄对照组比较,用方差分析检验差别的显著性。见到结扎后各组血清睾酮(T)水平无显著性改变,血清促黄体激素(LH)及卵泡刺激素(FSH)水平只有30～39岁结扎5年与10年的有显著性改变,但作者提出这些改变随年龄与扎后年数的增长也将消失。故认为输精管结扎后3～20年(30～65岁)对垂体-性腺轴无严重影响。
In this paper, we compared the long-term effects of vasectomy on the pituitary-gonad axis by comparing between groups. 289 in the control group and 515 in the ligation group. Both groups were 30 to 65 years old, and the number of years after ligation was 3 to 25 years. The differences were statistically analyzed by analysis of variance with the same age group. There were no significant changes of serum testosterone (T) levels after the ligation in all groups. Serum luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels were only significantly changed after 5 years and 10 years of ligation between 30 and 39 years The authors suggest that these changes will disappear with age and years of growth. Therefore, 3 to 20 years after vasectomy (30 to 65 years of age) have no serious effect on the pituitary-gonadal axis.