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目的:探讨ω-3鱼油脂肪乳剂(尤文)对严重创伤患者全身炎症反应综合征(SIRS)评分及多器官功能障碍综合征(MODS)发生率的影响。方法:将92例严重创伤患者随机分为治疗组和对照组,对照组采用常规治疗,治疗组在常规治疗的基础上加用ω-3鱼油脂肪乳剂100mL静脉滴注,qd,疗程5～7d。于入院d1,3,5对患者进行SIRS评分,判断MODS发生率,并对两组患者的结果进行比较。结果:治疗组在SIRS评分转归及MODS发生率明显低于对照组(P<0.05)。结论:ω-3鱼油脂肪乳剂对严重创伤患者有明显疗效。
Objective: To investigate the effect of omega-3 fish oil emulsion (Juventus) on the incidence of systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) in patients with severe trauma. Methods: Ninety-two patients with severe trauma were randomly divided into treatment group and control group. The control group was treated by conventional therapy. The treatment group was given 100 mL omega-3 fish oil emulsion on the basis of routine treatment, qd for 5-7 days . SIRS scores were recorded on admission d1,3,5 to determine the incidence of MODS. The results of two groups of patients were compared. Results: The SIRS score and the incidence of MODS in the treatment group were significantly lower than those in the control group (P <0.05). Conclusion: Omega-3 fish oil emulsion has obvious curative effect on severe trauma patients.