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双异丙吡胺的药理作用类似奎尼丁,据载副作用较轻而短暂,减量即可消失,一般剂量也不会引起QT间期延长及奎尼丁样晕厥。我们试用此药代替奎尼丁对6例慢性心房纤颤患者进行复律,结果2例成功,3例因副作用大而停药,1例发生快速室性心律失常死亡。现报告如下。
The pharmacological effects of disopyramide is similar to that of quinidine, it contains less side effects and short-term, loss can disappear, the general dose will not cause QT prolongation and quinidine-like syncope. We tried this drug instead of quinidine in 6 patients with chronic atrial fibrillation cardioversion, the results of 2 cases of success, 3 cases due to large side effects and withdrawal, 1 case of rapid ventricular arrhythmia death. The report is as follows.