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目的:讨论儿童重症监护病房中血清降钙素原的应用价值,为日后的临床检验工作提供参考。方法:选择2011年3月-2013年9月梧州市人民医院收治的重症肺炎患者70例为观察组;选择同期于广西梧州市人民医院进行健康体检的60例健康儿童为对照组,对两组儿童实施血清降钙素原检查,对比两组儿童在入院1 d,入院3 d的临床指标。结果:经过临床统计,观察组患儿当中,细菌性肺炎患儿入院1 d的指标为(3.55±1.57)ng/m L,入院3 d的指标为(3.32±1.06)ng/m L;病毒性肺炎患儿入院1 d的指标为(0.13±0.15)ng/m L,入院3 d的指标为(0.13±0.04)ng/m L;支原体肺炎患儿入院1 d的指标为(0.22±0.14)ng/m L,入院3 d的指标为(0.20±0.07)ng/m L。对照组儿童入院1 d的指标为(0.10±0.06)ng/m L,入院3 d的指标为(0.10±0.06)ng/m L,两组儿童比较,差异有统计学意义(P<0.05)。结论:对于重症监护病房中的儿童来说,对其给予血清降钙素原的检验,可对儿童重症肺炎的早期鉴别、诊断、判断病情严重程度等提供帮助,并且为临床药物应用提供了可靠的依据。
Objective: To discuss the value of serum procalcitonin in children intensive care unit and to provide reference for future clinical examination. Methods: Seventy patients with severe pneumonia admitted to Wuzhou People’s Hospital from March 2011 to September 2013 were selected as the observation group. Sixty healthy children undergoing physical examination in Wuzhou People’s Hospital of Guangxi during the same period were selected as the control group. Children performed serum procalcitonin examination, compared two groups of children on admission 1 d, 3 d hospital admission clinical indicators. Results: According to the clinical statistics, the index of children with bacterial pneumonia was (3.55 ± 1.57) ng / m L for 1 d on admission and (3.32 ± 1.06) ng / m L for 3 days after admission in the observation group. The virus The index of children with Pneumonia at 1 day after admission was (0.13 ± 0.15) ng / m L and (0.13 ± 0.04) ng / m L at 3 days after admission. The index of children with mycoplasma pneumonia 1 day after admission was (0.22 ± 0.14 ) ng / m L, and the index of 3 days after admission was (0.20 ± 0.07) ng / m L. The index of the first day of admission was (0.10 ± 0.06) ng / m L in the control group and (0.10 ± 0.06) ng / m L on the third day of admission, the difference was statistically significant (P <0.05) . CONCLUSIONS: For children in intensive care units, testing of their serum procalcitonin may provide early support in identifying, diagnosing, and determining the severity of severe pneumonia in children, and provides a reliable basis for clinical drug use The basis.