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目的探讨妊娠期肝内胆汁淤积症(ICP)并子痫前期对母儿的影响。方法选择2004年1月～2007年12月在我院住院诊断为ICP产妇86例,其中并子痫前期9例(组Ⅰ),无合并症的77例(组Ⅱ),分析围产结局。结果组Ⅰ羊水粪染、早产、剖宫产、低体重儿、胎儿宫内窘迫、新生儿窒息、围产儿死亡高于组Ⅱ,差异有显著性,但产后出血无显著差异。结论ICP并子痫前期围产病率增加,应及早诊治,改善围产预后。
Objective To investigate the effect of intrahepatic cholestasis of pregnancy (ICP) on preterm and preeclampsia. Methods From January 2004 to December 2007, 86 pregnant women with ICP were diagnosed as hospitalized in our hospital, including 9 preeclampsia patients (group Ⅰ) and 77 patients without complications (group Ⅱ). The perinatal outcome was analyzed. Results Group Ⅰ, meconium-stained amniotic fluid, cesarean section, low birth weight, fetal distress, neonatal asphyxia and perinatal mortality were higher than those in group Ⅱ, but the difference was significant, but there was no significant difference in postpartum hemorrhage. Conclusion ICP and pre-eclampsia perinatal rate increased, early diagnosis and treatment, improve perinatal outcome.