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顺铂(DDP)是近年来应用于临床的重要抗癌新药。国外文献报道用DDP治疗恶性腔内积液,效果良好,国内报道尚少。自1991年1月～1992年1月,作者用DDP腔内注射治疗恶性腔内积液11例,取得一定疗效,现报道如下。一、病例情况本组病例均为我院收治的经病理学证实为恶性肿瘤、且胸水或腹水中查到癌细胞者。11例中男7例,女4例,年龄39～71岁,平均56.3岁。其中胸水8例(肺鳞癌3例、肺腺癌2例、乳癌2例,神经纤维肉瘤1例),腹水3例(胃癌术后复
Cisplatin (DDP) is an important new anti-cancer drug that has been used clinically in recent years. The foreign literature reported that DDP was used to treat malignant intraluminal effusions and the results were good. There were few domestic reports. From January 1991 to January 1992, the author used DDP intraluminal injection in the treatment of malignant effusion in 11 cases and achieved certain curative effects. The following are reported. I. Cases This group of cases were all malignant tumors confirmed by pathology in our hospital and were found in pleural effusion or ascites. In 11 cases, there were 7 males and 4 females, aged 39-71 years, with an average of 56.3 years. There were 8 cases of pleural effusion (3 cases of squamous cell carcinoma, 2 cases of lung adenocarcinoma, 2 cases of breast carcinoma, 1 case of neurofibrosarcoma), and 3 cases of ascites (postoperative reoperation of gastric cancer).