百草枯是一种高效、广谱、价廉且对环境污染小的有机杂环类接触性除草剂。该农药于1882年合成,随后发现其具有氧化还原与除草特性;1962年起百草枯作为除草剂,逐渐被国内外广泛使用[1]。急性百草枯中毒是农药中毒的最常见类型,以口服中毒最常见(占90%以上),大面积皮肤污染以及呼吸道吸入兼皮肤吸收也可致全身中毒[2-3]。急性百草枯中毒迄今无特效解毒剂,病死率高达73.4%~87.8%[4]。为了诊断 Paraquat is an organic heterocyclic contact herbicide with high efficiency, broad spectrum, low cost and little environmental pollution. The pesticide was synthesized in 1882 and was subsequently found to have redox and herbicidal properties. From 1962, paraquat was widely used as a herbicide at home and abroad [1]. Acute paraquat poisoning is the most common type of pesticide poisoning. Oral poisoning is the most common (over 90%), with extensive skin contamination and respiratory tract ingestion and skin absorption, which can also cause systemic poisoning [2-3]. Acute paraquat poisoning so far no specific antidote, case fatality rate as high as 73.4% ~ 87.8% [4]. In order to diagnose