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目的:比较两种抗菌药在本院小儿室间隔缺损围手术期中应用的疗效及经济学差异。方法:回顾性分析2011年本院行室间隔缺损手术病历351份,按预防性使用抗菌药品种分为头孢呋辛组(176例)和头孢美唑组(175),统计两组的相关数据并进行比较分析。结果:两组患者的抗菌药日均费用、抗菌药总费用指标差异有统计学意义(P<0.05);头孢呋辛组较头孢美唑组抗菌药日均费用和抗菌药总费用分别节省约42元和271元。两组患者术后感染率差异无统计学意义。结论:头孢呋辛较头孢美唑在经济学方面有优势,可以有效降低医疗费用,减轻患者的经济负担
Objective: To compare the curative effects and economic differences between two antibacterials during perioperative period of ventricular septal defect in our hospital. Methods: A retrospective analysis of 351 cases of ventricular septal defect surgery in our hospital in 2011 was divided into cefuroxime group (176 cases) and cefmetazole group (175 cases) according to prophylactic use of antibacterials. Statistics data of the two groups And comparative analysis. Results: The average daily cost of antibacterials and the total cost of antibacterials in both groups were statistically significant (P <0.05). The mean daily cost of antibacterials in cefuroxime group and the total cost of antibacterials were saved 42 yuan and 271 yuan. There was no significant difference in postoperative infection rates between the two groups. Conclusion: Cefuroxime has more economic advantages than cefmetazole, which can effectively reduce medical costs and reduce the financial burden on patients