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已知色氨酸是脑内5-羟色胺(5-HT)生物合成的前体,由血液转运入脑,但它在脑内的浓度低于色氨酸羟化酶(Tryptophan Hydroxylase)亲和力所需要的浓度。本文作者已证实,5-HT 能系统的正常功能是实现针刺镇痛的必需条件,针刺过程能激发脑内5-HT 能神经元的活动,使5-HT 生物合成增加,它的代谢产物5-羟吲(?)醋酸(5-HIAA)明显升高。那么,针刺镇痛过程是否也激发血脑色氨酸的转运功能,以保持脑内5-HT 能神经元正常活动的需要。本文针对这问题,在针刺镇痛后,分别测定血和脑色
Tryptophan is known to be a precursor of 5-hydroxytryptamine (5-HT) biosynthesis in the brain that transports blood from the brain into the brain, but its concentration in the brain is lower than that required for the affinity of Tryptophan Hydroxylase concentration. The authors have demonstrated that the normal function of the 5-HT system is a necessary condition for acupuncture analgesia. The acupuncture process can stimulate the activity of 5-HT neurons in the brain, increase the 5-HT biosynthesis, and its metabolism The product 5-hydroxyindole (?) Acetate (5-HIAA) was significantly increased. So, whether the acupuncture analgesia process also triggers the transport of blood tryptophan to maintain the normal activity of 5-HT neurons in the brain. This article aims at this problem, after acupuncture analgesia, were measured blood and brain color