一般认为腹部恶性肿瘤转移到肝脏即无治愈希望。现已证实,大肠癌肝转移并非全身性播散,较多病例在一定时间内转移仅限于肝脏,而且治疗效果均较好,对此应采取积极治疗。现将我们收治的病例报道如下。材料和方法1990年～1991年我们对4例大肠癌肝转移和6例无肝转移的中、晚期直肠癌进行门静脉置管化疗。男9例、女1例,平均年龄41岁(21岁～67岁)。肝转移组中3例直肠癌、1例结肠肝曲癌,均经手术前B超、CT证实,剖腹探查因肝广泛转移无法切除,原发灶均行切除。6例预防性用药者均为直肠癌,其中4例癌侵犯肠管近一周,深肌层、浆膜层及淋巴受侵犯。余2例癌肿侵犯肠管大于1/2周,并侵及深肌层或浆膜层,淋巴未受累,均为中、低分化腺癌。 It is generally believed that there is no hope of cure for the metastasis of the abdominal malignancy to the liver. It has been confirmed that the liver metastases of colorectal cancer is not systemic dissemination, and that more cases are metastasized to the liver within a certain period of time, and the therapeutic effects are good. Therefore, active treatment should be taken. The cases we have received are reported below. Materials and Methods From 1990 to 1991, we performed portal vein catheterization chemotherapy for 4 cases of colorectal cancer liver metastasis and 6 cases of liver metastases without middle and late rectal cancer. There were 9 males and 1 female, with an average age of 41 years (21 to 67 years old). In the liver metastasis group, 3 cases of rectal cancer and 1 case of colonic hepatic squamous cell carcinoma were confirmed by pre-operative B-ultrasonography and CT. The laparotomy was not performed due to extensive metastasis of the liver, and the primary tumor was removed. All 6 cases of preventive medications were rectal cancers, of which 4 cases of cancer invaded the intestine for nearly a week, and deep muscle layer, serosa and lymph were invaded. In the remaining 2 cases, the tumors invaded the intestine for more than 1/2 week and invaded the deep muscle or serosal layer. Lymph was not involved and both were moderately-differentiated adenocarcinomas.