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目的：观察中西医结合疗法对急性脑梗塞患者治疗前后血清可溶性血管细胞粘附分子（ｓＶＣＡＭ－１）的变化水平。方法：中西药组采用西医常规疗法加破瘀通络汤治疗，西药组采用西医常规疗法，采用酶联免疫法检测治疗前后患者血清可溶性血管细胞粘附分子（ｓＶＣＡＭ－１）水平。结果：中西药组及西药组治疗前ｓＶＣＡＭ－１水平与正常对照组比较明显增高（Ｐ＜００５）；治疗后两组ｓＶＣＡＭ－１水平均有明显下降（Ｐ＜００５）；而中西药组降低较西药组明显（Ｐ＜００５），与正常对照组比较，无显著性差异（Ｐ＞００５）。结论：提示中西医结合疗法治疗本病的作用机理与调节机体的免疫状态有关。
Objective: To observe the changes of serum soluble vascular cell adhesion molecule (sVCAM-1) in patients with acute cerebral infarction before and after treatment with traditional Chinese and western medicine. Methods: The traditional Chinese medicine and western medicine group was treated with Tongyu Tongluo Decoction. The western medicine group was treated with conventional western medicine. The level of soluble vascular cell adhesion molecule (sVCAM-1) was measured by enzyme-linked immunosorbent assay before and after treatment. Results: The levels of sVCAM-1 in Chinese medicine group and western medicine group before treatment were significantly higher than those in normal control group (P <005). The levels of sVCAM-1 in both groups decreased significantly (P <005) Compared with western medicine group, Chinese medicine group and Western medicine group decreased significantly (P <005), but there was no significant difference (P> 005) compared with normal control group. Conclusion: It is suggested that the mechanism of action of Integrative Medicine in treating this disease is related to the regulation of immune status.