Hadju—Cheney 综合征又名颅骨发育不良伴肢端溶骨症,遗传性骨发育不全和骨关节齿发育不良等,我院收洽一例报告如下:患者女,28岁,河南驻马店人,住院号1710。因指,趾渐进性粗短,腰背酸痛,咳喘23年住院。5岁发现指、趾端开始粗大,以后指、趾变短,爪甲增厚变小,不能作精细及稍重劳动,活动稍重则局部痛疼。腰背经常酸痛,11岁、22岁两次因提物腰部扭伤。23岁牙齿松动,相继于25岁全部脱 Hadju-Cheney syndrome, also known as skull dysplasia with limb osteolytic disease, hereditary achondroplasia and bone and joint dentition dysplasia, our hospital received a report as follows: The patient female, 28 years old, Henan Zhumadian, hospital number 1710. Because refers to, toe gradual stubborn, back pain, cough and asthma hospitalization for 23 years. 5-year-old found that the toe began to coarse, later refers to the toes become shorter, thicker nail smaller, can not be fine and a little heavy work, activities slightly heavier local pain. Back pain often, 11 years old, 22 years old twice because of mention waist sprain. 23-year-old teeth loose, one after another at 25 years of age all off