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肝门区胆管癌的预后很差.影响预后最重要的因素之一为癌肿侵犯肝内胆管周围的淋巴管和神经周间隙.晚近,Hagihara等开拓出一种抗癌药新剂型——吸附于活性炭的丝裂霉素C(MMC-AC).它具有特定的亲淋巴性,并能逐渐均匀地释放出MMC.设想如果将MMC-AC注射到靠近肿瘤的肝门区胆管内,药物将选择性地被带到肿瘤附近和肝内胆管周围的淋巴
The prognosis of hilar cholangiocarcinoma is poor. One of the most important factors affecting prognosis is cancer invasion of lymphatic vessels around the intrahepatic bile ducts and perineural space. In the near future, Hagihara et al. developed a new dosage form of anticancer drugs—adsorption. Activated carbon mitomycin C (MMC-AC). It has a specific lymphotropic nature and can gradually and uniformly release MMC. It is envisaged that if MMC-AC is injected into the bile duct near the tumor in the hilus, the drug will Selectively brought to the vicinity of the tumor and lymphatics around the intrahepatic bile duct