论文部分内容阅读
目的分析左氧氟沙星所致不良反应及临床合理用药。方法选取2013年9月—2014年9月进贤县人民医院收治的左氧氟沙星所致不良反应患者59例,对其临床资料进行回顾性分析。结果 59例患者中21~60岁者50例(84.7%);给药剂量200~400mg有30例(50.8%);静脉滴注51例(86.4%),口服7例(11.9%),滴眼1例(1.7%);累及皮肤及其附件19例(32.2%),过敏性休克11例(18.6%),累及神经系统10例(16.9%);停药后症状消失40例(67.8%),经糖皮质激素治疗康复10例(16.9%),对症治疗后康复9例(15.3%)。结论使用左氧氟沙星时必须严格掌握药物适应证,结合患者性别、年龄、给药剂量、给药途径等合理使用,以减少不良反应的发生。
Objective To analyze the adverse reactions caused by levofloxacin and its clinical rational use. Methods 59 cases of adverse reactions caused by levofloxacin admitted to Jinxian People’s Hospital from September 2013 to September 2014 were selected and their clinical data were retrospectively analyzed. Results Fifty patients (84.7%) were 21 to 60 years old in 59 patients. Thirty patients (50.8%) received intravenous infusion of 200-400 mg, 51 (86.4%) were intravenously dripped and 7 patients (11.9% 1 case (1.7%) of the eyes, 19 cases (32.2%) of the skin and its appendages, 11 cases (18.6%) of the anaphylactic shock and 10 (16.9%) cases of the nervous system, 40 cases (67.8% ), 10 cases (16.9%) were treated with glucocorticoid, and 9 cases (15.3%) recovered after symptomatic treatment. Conclusion Levofloxacin must be strictly controlled when using drugs indications, combined with the patient’s gender, age, dosage, route of administration and other rational use, in order to reduce the incidence of adverse reactions.