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病人女 24岁。因肺结核用INH、RFP、PZA及SM常规量治疗3周后,出现恶心呕吐、黄疸而停用RFP及PZA,改用EMB。10天后全身出现散在斑丘疹,用抗过敏治疗无效乃停EMB,4天后体温达39℃,皮损加重,口腔粘膜破溃、糜烂、双眼结膜充血、阴道充血糜烂。化验:WBC9.6×10~9/L,N0.70,L0.16,E0.14。考虑为SM所致。乃停SM静脉滴注地塞米松每日15mg,2日后皮损开始减轻,2周消退。半月后,行SM皮试反应阴性,复注SM0.5,4小时左右再度发生上述过敏反
The patient is 24 years old. After three weeks of treatment of pulmonary tuberculosis with conventional INH, RFP, PZA and SM, nausea and vomiting, jaundice and disabled RFP and PZA to EMB. 10 days after the body appeared scattered rash, with anti-allergy treatment is invalid EMB, 4 days after the body temperature of 39 ℃, increased skin lesions, oral mucosal ulceration, erosion, conjunctival hyperemia, vaginal congestion erosion. Laboratory: WBC9.6 × 10 ~ 9 / L, N0.70, L0.16, E0.14. Considered SM. Stop SM intravenous dexamethasone daily 15mg, 2 days after the lesion began to reduce, 2 weeks subsided. Half a month later, the line SM skin test negative, re-injection SM0.5, about 4 hours or so recurrence of the above allergy