目的:探讨Ｗａｌｌｅｎｂｅｒｇ综合征的临床及影像学特点。方法:对２２例Ｗａｌｌｅｎｂｅｒｇ综合征的临床资料及头颅ＣＴ、ＭＲＩ检查作回顾性分析。结果:ＣＴ扫描不能显示责任病灶。２２例ＭＲＩ检查中１９例(８６．４%)延髓显示异常信号。其中７例合并小脑梗死,３例(１３．６%)未见异常信号。结论:交叉性感觉障碍,构音、吞咽障碍,眩晕,同侧Ｈｏｒｎｅｒ征及同侧肢体共济失调是最常见的临床特征,部分病例伴第６、７、８脑神经或锥体束受累的表现。目前影像学检查首选ＭＲＩ,小脑区梗死不容忽视。 Objective: To investigate the clinical and imaging features of Wallenberg syndrome. Methods: The clinical data of 22 cases of Wallenberg syndrome and cranial CT and MRI were retrospectively analyzed. Results: The CT scan did not show responsible lesions. In 22 cases of MRI examination, 19 cases (86.4%) of the medulla showed abnormal signals. Among them, 7 cases had cerebellar infarction and 3 cases (13.6%) showed no abnormal signal. CONCLUSIONS: Crosstalk, dysarthria, dysphagia, dizziness, ipsilateral Horner syndrome and ipsilateral limb ataxia are the most common clinical features. Some patients with involvement of cranial nerves or pyramidal tract of 6th, 7th and 8th which performed. The current imaging examination preferred MRI, cerebellar infarction can not be ignored.