原发性肝癌(简称 PHC)的病因与发病机理尚未完全搞清,但已知其与乙型病毒性肝炎及肝硬化的关系密切。其他因素如黄曲霉毒素(AFB_1)、饮酒、饮水等与乙型肝炎病毒协同致PHC的关系仍在深入研究。有关肝癌病因预防我国已在高发区采取了“管水、管粮、防肝炎”的措施,但重要的是如何早期检出、早期诊断及早期治疗问题。本文根据临床经验, The etiology and pathogenesis of primary liver cancer (abbreviated as PHC) have not been fully understood, but it is known that it has a close relationship with hepatitis B and cirrhosis. Other factors such as the relationship between aflatoxin (AFB_1), drinking and drinking and hepatitis B virus causing PHC are still being studied. Prevention of liver cancer causes China has adopted measures to “control water, manage grain, and prevent hepatitis” in high-risk areas. However, it is important how early detection, early diagnosis, and early treatment are needed. This article is based on clinical experience.