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碳酸锂是治疗躁狂型抑郁症的药物,对造血系统、内分泌系统、消化系统的疾病也有明显的疗效;此外,对月经过多、痛经、经前期紧张症等均有良效。由于应用广泛,因此,要注意与其他药物合并应用的相互作用。1、碳酸锂与钠盐(氯化钠、碳酸氢钠等)合用:二者有比例制约的特性,当钠盐摄取量减少时,锂盐的浓度可提高,当锂盐的浓度到一定的水平时,可引起中毒。服用过多的钠盐,可促进锂盐的排除,故锂盐中毒时,可多服钠盐。对要求低的钠饮食的肾脏病人,不宜服用锂盐。2、碳酸锂与四环素合用:四环素可抑制锂盐的排泄,使血药浓度增高,可致锂盐蓄积中毒。
Lithium carbonate is a medicine for the treatment of manic depression and has obvious curative effect on hematopoietic system, endocrine system and digestive system diseases. In addition, lithium carbonate has good effect on menorrhagia, dysmenorrhea and premenstrual tense disorder. Due to the wide range of applications, therefore, pay attention to the interaction with other drug combination applications. 1, lithium carbonate and sodium (sodium chloride, sodium bicarbonate, etc.) combined: the two have a proportional control characteristics, when the sodium intake decreased, the lithium salt concentration can be increased, when the lithium salt concentration to a certain Level, can cause poisoning. Too much sodium can promote the elimination of lithium salts, so lithium poisoning, can serve more sodium. Kidney patients who require a low sodium diet should not take lithium salts. 2, lithium carbonate and tetracycline combination: tetracycline can inhibit the excretion of lithium salts, blood concentration, can cause lithium poisoning.