小儿胰岛细胞增殖症(nesidioblastosis)又称婴儿、儿童高胰岛素血症。特点是高胰岛素血症所致低血糖,延误治疗可导致严重的脑组织损害。及早手术是治疗本症的关键。葡萄糖是新生儿期脑耗氧代谢的主要物质,生后1年内脑发育最快,葡萄糖的利用率也最大。供给脑的能量减少,将直接影响脑的代谢和使细胞结构受损。年龄越小,低血糖的危害越大,有些脑损害是不可逆的。本病的发生是因在胚胎期胰腺导管上皮萌芽生长产生新的内分泌细胞,在胰岛外的胰腺组织中有分泌胰岛素的 B 细胞。有认为是分泌胰岛素的 B 细 Pediatric islet cell proliferation (nesidioblastosis), also known as infants, children hyperinsulinemia. Is characterized by hyperinsulinemia caused by hypoglycemia, delayed treatment can lead to serious brain damage. Early surgery is the key to the treatment of this disease. Glucose is the main substance in neonatal cerebral oxygen consumption metabolism, the fastest brain development within one year after birth, glucose utilization is also the largest. The reduction of energy supplied to the brain will directly affect the metabolism of the brain and damage the cellular structure. The younger, the greater the harm of hypoglycemia, some brain damage is irreversible. The occurrence of this disease is due to embryonic pancreatic duct epithelial germination and growth to produce new endocrine cells in pancreatic tissue outside the pancreatic insulin-secreting B cells. There is thought to be secreting insulin B fine