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目的探讨65例腹腔镜结肠癌根治术的疗效及安全性。方法选择2012年2月至2014年1月间收治的130例结肠癌患者进行研究。按照随机数表法均分为观察组和对照组。观察组65例患者采用腹腔镜下结肠癌根治术治疗,对照组65例患者采用常规的开腹手术。比较两组患者的各项治疗指标(切口长度、术中出血量、手术时间、排气时间、住院时间)、并发症发生率(切口发生感染率、吻合口出现出血率、切口脂肪发生液化率、不完全肠梗阻率、总发生率)以及复发率。结果观察组患者的手术时间与对照组差异无统计学意义(P>0.05);观察组患者的切口长度明显短于对照组,差异有统计学意义(P<0.001);观察组患者的出血量少于对照组,差异有统计学意义(P<0.001);观察组的术后排气时间与住院时间均短于对照组,差异有统计学意义(P<0.001)。观察组和对照组患者的并发症总发生率分别为9.2%与30.8%,差异有统计学意义(P=0.002)。观察组和对照组患者的复发率分别为3.1%和13.9%,差异有统计学意义(P<0.05)。结论腹腔镜下结肠癌根治术的手术效果良好,安全性较高,预后良好,值得临床推广。
Objective To investigate the efficacy and safety of 65 cases of laparoscopic radical mastectomy. Methods A total of 130 patients with colon cancer who were admitted between February 2012 and January 2014 were enrolled in this study. According to random number table method were divided into observation group and control group. Sixty-five patients in the observation group were treated with laparoscopic radical resection of colon cancer, while 65 patients in the control group received conventional laparotomy. Comparing the treatment indexes (incision length, intraoperative blood loss, operation time, exhaust time and hospital stay), the incidence of complications (incision infection rate, bleeding rate at anastomotic site, liquefaction rate of incision fat , Incomplete intestinal obstruction rate, total incidence), and relapse rate. Results There was no significant difference between the observation group and the control group (P> 0.05). The incision length of the observation group was significantly shorter than that of the control group (P <0.001). The bleeding volume Less than the control group, the difference was statistically significant (P <0.001); the observation group postoperative exhaust time and hospital stay were shorter than the control group, the difference was statistically significant (P <0.001). The total complication rates in observation group and control group were 9.2% and 30.8%, respectively, with significant difference (P = 0.002). The recurrence rates in observation and control groups were 3.1% and 13.9%, respectively, with significant differences (P <0.05). Conclusions Laparoscopic surgery for colon cancer is effective, safe and has a good prognosis. It is worthy of clinical promotion.