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目的探究盐酸米诺环素在牙周病中的运用效果。方法将2010年1月-2012年1月接受牙周治疗的我院患者76例随机分为两组各38例,观察组用盐酸米诺环素软膏治疗,对照组用碘甘油治疗,观察两组患者用药前后的临床症状、不良反应及疗效。结果观察组总有效率97.37%,高于对照组的78.94%(χ2=4.5373,P<0.05)。结论盐酸米诺环素在牙周病的应用可有效抑制炎症反应,安全可靠。
Objective To investigate the effect of minocycline hydrochloride in periodontal disease. Methods From January 2010 to January 2012, 76 patients in our hospital who underwent periodontal treatment were randomly divided into two groups (n = 38). The observation group was treated with minocycline hydrochloride ointment while the control group was treated with iodine glycerol. Group before and after treatment of patients with clinical symptoms, adverse reactions and efficacy. Results The total effective rate in observation group was 97.37%, which was higher than 78.94% in control group (χ2 = 4.5373, P <0.05). Conclusion The application of minocycline hydrochloride in periodontal disease can effectively inhibit the inflammatory reaction and is safe and reliable.