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本文报告内镜荧光检测诊断消化道癌94例的临床经验。在患者静注HDP后,当内镜发现病灶,经石英纤维导入氩激光照射病灶后,通过内镜及微光象增强仪观察。如荧光阳性,提示病变恶性,阴性提示良性。并用切除癌标本13例作模拟试验。对81例临床受检者的观察,荧光检测结果与良恶性病变符合77例(95.66%),假阳性3例,未定1例。本文讨论了假阳性的可能原因与临床应用的评价。
This article reports the clinical experience of endoscopic fluorescence detection in the diagnosis of 94 cases of gastrointestinal cancer. After the patient was injected with HDP intravenously, the lesion was found by endoscopy. After being introduced into the lesion with argon laser light, the quartz fiber was observed by endoscopy and microphoto enhancement. If the fluorescence is positive, the lesion is malignant, and the negative is benign. 13 cases of cancer specimens were used as simulation tests. Among the 81 clinical subjects, the fluorescence results were consistent with benign and malignant lesions in 77 cases (95.66%), false positives in 3 cases, and undetermined in 1 case. This article discusses the possible causes and clinical applications of false positives.