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本文100例中晚期恶性肿瘤病人,均经病理证实。在实行常规化疗,病员外周血象连续二次实验室检查均减少者,脐血组60例经静脉输注3~4小时内脐血1个单位(100ml),最少输注1次,最多输注4次,平均2.2次,对照组40例口服利血生,鲨肝醇、维生素B_4及配合中药升血汤。结果:脐血组有效率83.3%,显著高于对照组33.3%,两组比较P<0.05,而副作用少。认为:3~4小时内新鲜脐血有效成份破坏较少,可能含有少量造血干细胞,且重建造血功能能力较成人骨髓强,达到解除病人因化疗药物所致骨髓抑制有明显的疗效。脐血具有来源丰富、容易收集、保存,具有良好的临床应用价值。
In this paper, 100 patients with advanced malignant tumors were confirmed by pathology. In the implementation of conventional chemotherapy, the patient’s peripheral blood as two consecutive laboratory tests were reduced, umbilical cord blood group of 60 intravenous infusion of 3 to 4 hours within 1 to 4 hours of cord blood (100ml), at least 1 infusion, up to infusion 4 times, an average of 2.2 times, the control group of 40 cases of oral reserpine, batyl alcohol, vitamin B_4 and with traditional Chinese medicine Sheng Xue Tang. Results: The effective rate of cord blood group was 83.3%, which was significantly higher than that of control group (33.3%), P <0.05, but less side effects. That: 3 to 4 hours less damage to the active ingredient of fresh cord blood, may contain a small amount of hematopoietic stem cells, and reconstruction of hematopoietic function stronger than adult bone marrow to achieve the lifting of patients with chemotherapy-induced bone marrow suppression had a significant effect. Cord blood is rich in source, easy to collect, save, with good clinical value.