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最近由于受大鼠和灵长类下丘脑内高浓度 P 物质(Substance P,SP)观测结果的启发,对其在下丘脑-脑下垂体(HP)轴内的神经内分泌作用给予了更密切的关注。本文概述 SP 影响下丘脑肽释放的证据,并总结它在垂体前叶水平的作用。
Recently, the neuroendocrine effects in the hypothalamic-pituitary (HP) axis have been given more attention due to the discovery of high concentrations of Substance P (SP) in rat and primate hypothalamus . This article outlines the evidence that SP affects hypothalamic peptide release and summarizes its role in the anterior pituitary gland.