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自杂交瘤和单克隆抗体技术问世以来，人们一直尝试将该技术用于肿瘤治疗．抗体工程的进展使得人们能够对抗体分子进行改造，研制具有高亲和力和特异结合力的基因工程抗体．同时人们对细胞内蛋白传导信号也有了更深入了解，从而可将基因工程抗体导向不同的亚细胞区室．上述两项
Since the advent of hybridoma and monoclonal antibody technology, people have been trying to use this technology for cancer treatment. Advances in antibody engineering have allowed people to modify antibody molecules and develop genetically engineered antibodies with high affinity and specific binding capacity. At the same time, people have a deeper understanding of intracellular signal transduction pathways, so that genetic engineering antibodies can be directed to different subcellular compartments. The above two items